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Estradiol is a synthetic estrogen; a female sex hormone that regulates organs like the uterus, pituitary, and adrenal glands. It’s used in various medications for both men and women.
Estradiol is a female estrogen hormone that is prescribed to treat menopause symptoms such as hot flashes, night sweats, vaginal dryness/itching, irregular periods, and mood swings. Besides, this medication prevents bone fractures (osteoporosis) and reduces the risk of heart attacks. Estradiol vaginal cream is indicated for vaginal atrophy associated with menopause. This medicine may also be used to treat other conditions as determined by your doctor.
The dosage of Estradiol prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label. Estradiol may be taken with or without food.
If your physician has instructed or directed you to take Estradiol medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.
The normal levels for estradiol are: 30 to 400 pg/mL for premenopausal women and 0 to 30 pg/mL for postmenopausal women.
Estradiol, the most potent form of estrogen, is a steroid hormone that acts as a powerful messenger within the body. Its primary action involves binding to specific receptors inside and on the surface of cells. When it binds to nuclear receptors (ERα and ERβ), it directly influences gene transcription, a slower process that controls the production of proteins responsible for long-term effects like bone growth and reproductive function. Additionally, it can bind to membrane receptors (GPER), triggering a cascade of rapid cell signaling for more immediate responses.
This dual mechanism allows estradiol to have a widespread impact on numerous bodily systems. Its effects are crucial for the menstrual cycle, bone and cardiovascular health, mood regulation, and cognitive function. By influencing cells throughout the body, estradiol plays a vital role in maintaining overall health and vitality for both men and women.
As a HormoneNexus patient, you’ll be supported along your entire wellness journey by our medical team of board certified doctors.
MD
Estradiol Side Effects
Like any medication, Estradiol may cause side effects in some individuals. Common side effects may include:
Other possible side effects may include:
Hormone replacement therapy (HRT), also referred to as menopausal hormone therapy (MHT), is an estrogen- and/or progesterone-containing medication meant to replace hormones the body stops producing during perimenopause or the menopausal transition.
Your HormoneNexus physician will assess your individual situation and determine the proper protocol.
